Antiviral Efficacy of Citra-kill∨®, Disinfectant Solution Against Avian Influenza Virus
2012
Cha, C.N., Gyeongsang National University, Jinju, Republic of Korea | Lee, Y.E., Gyeongsang National University, Jinju, Republic of Korea | Kang, I.J., Gyeongsang National University, Jinju, Republic of Korea | Yoo, C.Y., Gyeongnam Provincial Namhae College, Namhae, Republic of Korea | Park, E.K., Kosin University, Busan, Republic of Korea | An, S.J., Inje University, Gimhae, Republic of Korea | Kim, S., Gyeongsang National University, Jinju, Republic of Korea | Lee, H.J., Gyeongsang National University, Jinju, Republic of Korea
Highly pathogenic avian influenza virus (HPAIV) is already panzootic in poultry and caused a considerable economic loss in poultry industry. In addition, HPAIV continues to cross species barriers to infect humans and other mammals, often with fatal outcomes. In this study, the virucidal efficacy of Citra-kill∨® composed to quaternary ammonium chloride and citric acid was investigated against avian influenza H9N2 virus (AIV). A virucidal efficacy was determined with the viability of AIV contacted with the disinfectant in the allantoic membrane of chicken embryos. Citra-kill∨® and AIV was reacted on the distilled water (DW), hard water (HW) or organic matter suspension (OM) condition. On DW condition, AIV was inactivated with 2,000 fold dilutions of Citra-kill∨®. When the antiviral effect on HW condition was evaluated, the antiviral activity of the disinfectant showed on 1,500 fold dilutions against AIV. With the investigation of the antiviral effect of the disinfectant on OM condition, AIV was inactivated on 500 fold dilutions of Citra-kill∨®. As Citra-kill∨® possesses virucidal efficacy against AIV, the disinfectant solution can be used to limit the spread of animal viral diseases.
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