Antihyperglycemic Effect of Water Extracts from Pleurotus cornucopiae-Containing alpha-Glucosidase Inhibitor
2016
Shin, J.W., Paichai University, Daejeon, Republic of Korea | Bae, S.M., Paichai University, Daejeon, Republic of Korea | Han, S.M., Paichai University, Daejeon, Republic of Korea | Lee, Y.H., Gyeonggi-do Agricultural Research and Extension Service, Gwangju, Republic of Korea | Jeong, Y.K., Gyeonggi-do Agricultural Research and Extension Service, Gwangju, Republic of Korea | Ji, J.H., Gyeonggi-do Agricultural Research and Extension Service, Gwangju, Republic of Korea | Lee, J.S., Paichai University, Daejeon, Republic of Korea
Following preparation of water extracts of Pleurotus cornucopiae fruiting body-containing alpha-glucosidase inhibitor, their antihyperglycemic effects were examined using streptozotocin-induced diabetic Sprague-Dawley (SD)-rats. The water extracts from Pleurotus cornucopiae showed dosage-dependant antihyperglycemic effects on the streptozotocin-induced diabetic SD-rats after oral administration to 120 min on the short time test and 4 days on the long time test, respectively. The water extracts from Pleurotus cornucopiae fruiting body showed dosage-dependent hypoglycemic action after administration to 120 min and 4 days in the SD-rat and streptozotocin-induced diabetic SD-rat.
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