Current Research Status and Potential Applications of Capsella bursa-pastoris (L.) Medik
2023
Ha, K.H. | Kim, J.A. | Lee, S.C. | Park, S.Y. | Kwon, S.J. | Lee, S.I. | Lee, J.Y.
BACKGROUND: Capsella bursa-pastoris (L.) Medik (Brassicaceae), commonly known as 'shepherd's purse', has a long history of use in traditional medicinal use in regions such as Korea, China, and Europe. Numerous studies have revealed its diverse pharmacological properties and identified various metabolites. METHOD AND RESULT: In this review, we analyzed numerous studies related to C. bursa-pastoris, which are currently underway. We examined genomic research that has enabled determination of genomic size and origin, as well as transcriptome studies conducted to investigate genes related to environmental stress. We discussed the pharmacological properties of this plant, including its validated anti-inflammatory, anti-oxidant, anti-cancer, and anti-hemorrhagic activities. We also reviewed the various metabolites, including phenols, flavonoids, and sulfur compounds, which have been identified in this plant. We also discuss the biosynthetic pathways of choline and glucosinolates which were investigated using Arabidopsis thaliana, a model plant belonging to the family Brassicaceae, as this research can facilitate future studies on C. bursa-pastoris. CONCLUSION: This review provides a comprehensively summarizes the research conducted on C. bursa-pastoris as a traditional resource for use in pharmaceutical applications and foods. This will contribute to future studies focused on enhancing the levels of valuable functional compounds from this plant.
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