Antioxidant and Skin Whitening Effects of Jeju Mango Kernel Extracts (Mangifera indica L. var. Irwin)
2022
Kang, J.W. | Lee, I.C.
The mango (Mangifera indica L.) is a tropical perennial fruit belonging to the genus Mangifera of the Anacardiaceae family, and the Irwin mango (Mangifera indica L. var. Irwin) variety is mainly grown on Jeju Island. In this study, a Jeju mango kernel extract (JMKE) was prepared using 70% ethanol. The antioxidant and tyrosinase inhibitory activity of JKME as well as its effects on melanin activation were investigated to determine its utility as a functional material. The study results indicated that DPPH radical scavenging activity was around 92.02±0.05%, while the ABTS scavenging activity was around 99.55±0.02%, at 50 μg/mL concentration of the JMKE. Tyrosinase inhibitory activity was observed to be directly proportional to the JMKE concentration, confirming its whitening activity. In melanocytes, JMKE at 100 μg/mL had a tyrosinase inhibitory activity of around 26.08%. This was the maximum concentration of JMKE at which it was non-cytotoxic. In addition, primary skin irritation tests revealed that JMKE is a hypoallergenic substance and is thus suitable for use as a functional material.
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