Treatment of mastitis with cefaclor and sparfloxacin - a comparative trial report
2001
Umakanthan, T. | Prabhakar, T.G. (Veterinary Dispensary, Uthamapalayam (India).)
In field causative agents of mastitis develop resistance due to many reasons; hence always there is a search for superior, economical and suitable antibiotic for mastitis treatment. A recent antibiotic "Cefaclor" and antibacterial "Sparfloxacin" were used in mastitis treatment. The results are compared in this trial. Cefaclor is a recent semisynthetic broad spectrum cefalosporin antibiotic, which is active against gram +ve and -ve aerobes and certain anaerobes except Pseudomonas species. Cefaclor acts by inhibiting cell wall synthesis. Sparfioxacin is a recent fluoroquinolone antibacterial, having broad spectrum action against gram +ve and -ve aerobes including certain anaerobes. Sparfloxacin acts by inhibiting the supercoiling activity of DNA gyras which is an essential enzyme for DNA replication.
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