Effect of dichlorvos on the brain and fat body cells of the adult Musca domestica L. (Muscidae: Diptera)
1997
Sharif, F. | Ali, F.A. (Punjab Univ., Lahore (Pakistan). Dept. of Zoology)
LD50 for dichlorvos was calculated to be 11.8 ppm after 24 hours of treatment. Of all the components of the brain the neurons were the most affected. They showed hypertrophy and pyknosis which ultimately led to the histolysis of the cells. Glial cells, although, not so severely affected, changed in their nuclear contents to some extent. Neural lamella thickened irregularly after treatment. The neuropile along with its glomerular bodies underwent vacuolization. The plasma membranes of the fat body cells ruptured after extensive vacuolization and the cytoplasmic content almost disappeared. The chromatin material darkened and became concentrated in the middle of the cells.
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