Malathion induced haematoxicity in chicks of fowl, Gallus domesticus
1997
Ali, S.S. | Arshad, M. | Ali, T. (Punjab Univ., Lahore (Pakistan). Dept. of Zoology)
An organophosphate insecticide, malathion was administered orally to chicks in three different doses i.e., 600, 400 and 250 mg/kg body wt./day for the total periods of 40 hours, 12 days and 4 weeks, respectively. The blood samples were collected following stipulated periods of 5, 10, 20 and 40 hours duration in short term experiment, at 3, 6 and 12 days in 1st long term experiment and at 2, 3 and 4 weeks in 2nd long term experiment and used for various haematological studies. In short term experiment, significant changes were found in MCV (15% and 10% decrease) and MCHC (13.09% and 14.1% increase) at 20 and 40 hours treatments. In 1st long term experiment the Hb increased by 16%, 12% and 21% at 3, 6 and 12 days. Similar rise was also found in 2nd long term experiment. MCHC increased at 12 days (20%) in 400 mg dose and at 3 and 4 week (16 and 13%, respectively) in 250 mg dose level. The WBC count showed persistent increase in all three treatments.
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