Gene diversity of ABO and rhesus blood group system in the population ofKarachi, Pakistan
2005
Imtiaz, F.,Baqai Medical Univ., Karachi (Pakistan). Dept. of Pathology)Sheikh,I.H
The ABO and Rhesus blood group systems remain the most important bloodgroup systems clinically. In order to provide gene frequency values for ABO andRh (D) alleles in the population belongs to the metropolitan area Karachi, 2630samples were collected for ABO and Rh (D) blood groups during the period of2004. Overall, 37.3% were blood group O, 27.8% were A, 28.9% were B and 6.1 %were belongs to AB blood group. The distribution of ABO blood groups did notdiffer significantly from those expected under the Hardy Weinberg Equilibrium.The proportions of the samples belonging to the various ABO blood groups did notvary significantly over the period of the study. Overall, gene frequencies for O, Aand B genes were found to be 0.607 plus minus 0.019, 0.200 plus minus 0.012 and0.212 plus minus 0.021 respectively.
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