Laboratoriumi majdiagnosztika lehetosegei kutyakban.
1996
Karsai F.
Hepatic laboratory diagnosis of dogs consists of biochemical and instrumental investigations (Table 1). Biochemical methods detect the functional disturbances of the organ, as well as the grade of damage of hepatocytes (Tables 2, 3 and 4) while the morphological changes can be detected by X-ray, ultrasonic examinations and hepatic biopsy (Table 5). In course of the general laboratory investigations, measurement of ALT, AP, total bilirubin, by chance also the measurement of the blood plasma level of ammonia and AST - by hepatic screening - the occurrence of diffuse hepatic changes can be detected (Table 6). However the target of individual hepatic diagnosis is to follow up the severity, character and tendency of hepatic changes. That can be carried out by repeated measurement of hepatocellular enzymes and AP-activity and even more by the determination of total bile acid level in the blood plasma, as well as carrying out the ammonia tolerance and BSP (bromosulphalein) tests. Of the instrumental investigations, ultrasonic examination and especially the hepatic biopsy controlled by ultrasonic examination are to be emphasized as the only safe methodology nowadays to precise the hepatic diseases in vivo.
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