Issledovanie nekotorykh nejrokhimicheskikh mekhanizmov vliyaniya zadnego gipotalamusa na ehlektricheskuyu aktivnost' bol' shikh polusharij perednego mozga i na vegetativnye reaktsii u kur.
1993
Baklavadzhyan O.G. | Pogosyan N.L. | Arshakyan A.V.
Effects of i.v. administration of N- and M-cholinergic blocking agents ganglerone and atropine and alpha- and beta-adrenergic blocking agents phentolamine and obsidan (propranolol) on reaction of desynchronisation of EEG and on autonomic reactions (arterial blood pressure, heart and respiratory rates) evoked by low- and high frequency stimulation of the posterior hypothalamus were studied in hens. It was shown that atropine induces a pharmacological dissociation of ascending and descending influences of the hypothalamus by blocking the desynchronizing mechanisms, of the upward discharge of the hypothalamus without any apparent changes of autonomic reactions. It was found that the effects of adrenoblocking agents are diametrically opposite to that of atropine in regard to the EEG component, as well as the autonomic components of hypothalamically induced activation reaction. Pecularities of evolutionary development of neurochemical structures of ascending and descending systems of the hypothalamus are discussed.
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