Investigation of oxidative stress in sheep bred in areas exposed to depleted uranium (DU) ammunition
2004
Aleksic, J. (University of Belgrade, Belgrade (Serbia and Montenegro). Faculty of Veterinary Medicine) | Lukic, S. | Jovic, S. | Kovacevic-Filipovic, M. | Vlaski, M. | Bozic, T. | Popovic, D. | Stevanovic, D.
The paper presents the preliminary results of the study on environmental and health effects due to the use of depleted uranium (DU) ammunition during NATO bombing of Yugoslavia in 1999. The blood samples of sheep were collected randomly in the region of Bujanovac, in 2003. To access the possible effects of DU on animal health, some of the relevant biochemical and hematological blood parameters were analyzed: concentration of RBC MDA (red blood cells malondialdehide), erythrocytes superoxide dismutase (SOD) activity, hemoglobin concentration and number of erythrocytes (Er). Functional activity of leucocytes (Le) was performed using NBT reduction and adhesion test. The results are considered in correlation with the data on the content of DU that entered the environment during the bombing. The obtained results on peripheral blood hematological and biochemical parameters indicated that animals were under violent oxidative stress. However, there were not enough data, especially on the content of DU in the environmental samples in the region (soils, vegetation, feed) to enable a conclusive correlation of the blood data with the effects of DU.
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