MORPHOLOGICAL CHANGES IN THE SPLEEN OF SHEEP DURING CULTIVATION WITH THE USE OF THE BIOSTIMULATOR «GAMAVIT» | МОРФОЛОГИЧЕСКИЕ ИЗМЕНЕНИЯ СЕЛЕЗЁНКИ ОВЕЦ В ПРОЦЕССЕ ВЫРАЩИВАНИЯ ПРИ ИСПОЛЬЗОВАНИИ БИОСТИМУЛЯТОРА «ГАМАВИТ»
2023
T. P. Shubina | N. V. Choporova | Т. П. Шубина | Н. В. Чопорова
The aim of the study was to analyze the dynamics of morphometric parameters of the sheep spleen in postnatal ontogenesis when feeding the biologically active drug «Gamavit». We studied macro- and micro-morphometric parameters: absolute weight, length, width, thickness, relative area of the parenchyma, its constituent elements - red and white pulp, as well as the relative area of the stroma. The material for the study was newborn, five and nine-month-old sheep from private farms in the Rostov region. We used macro- and micromorphometric techniques. In the experiment, a complex preparation «Gamavit» was used, which has an immunomodulatory and general biotonic effect. The drug applied prophylactically at a dose of 0.1 ml / kg of body weight to animals of the experimental group at the age of nine months for ten days. The authors studied the dynamics of morphological changes in the spleen of sheep when using a biologically active drug. The most significant increase in the studied morphometric parameters of the spleen in sheep was in the period from birth to five months: in the absolute weight, 14.3 times; the width and thickness grew the same 2.5 times, the least of all changed the length by 1.3 times. The relative area of the spleen parenchyma in sheep decreased with age, mainly due to a reduction in the area of the white pulp. It was found that the absolute indices of the lymphoid tissue of the spleen of sheep treated with the drug «Gamavit» were higher in all age periods in comparison with the indices of the animals of the control group, which indicates a positive effect of the drug.
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