Homochiral imidazolium-based dicarboxylate silver(i) compounds: synthesis, characterisation and antimicrobial properties
2022
Carrasco Carrasco, Carlos Jesús | Montilla Ramos, Francisco Javier | Álvarez González, Eleuterio | Galindo del Pozo, Agustín | Pérez Aranda, María | Pajuelo Domínguez, Eloísa | Alcudia Cruz, Ana | Universidad de Sevilla. Departamento de Química Inorgánica | Universidad de Sevilla. Departamento de Química Orgánica y Farmacéutica | Universidad de Sevilla. Departamento de Microbiología y Parasitología | Ministerio de Ciencia, Innovación y Universidades (MICINN). España | Junta de Andalucía
Complexes [Ag(LR)], 2 (LR = 2,2′-(imidazolium-1,3-diyl)di(2-alkylacetate)), were prepared by treatment of compounds HLR, 1, with Ag2O. They were characterised by analytical, spectroscopic (IR, 1H and 13C NMR and polarimetry) and X-ray methods (2c, 2c′ and 2e). In the solid state, these compounds are novel one-dimensional or two-dimensional coordination polymers in which silver(I) cations are connected via the chiral [LR]− anion with unprecedented coordination modes. The antimicrobial properties of these complexes were evaluated. 2a and 2b′ showed the best antimicrobial properties (minimal inhibitory concentrations and minimal bactericidal concentration) for Pseudomonas aeruginosa and Escherichia coli pathogens. Eutomers 2b′ and 2c′ showed slightly better antimicrobial properties than their respective enantiomers 2b and 2c.
Show more [+] Less [-]Ministerio de Ciencia, Innovación y Universidades (PGC2018-093443-B-I00 and PID2019109371GB-I00)
Show more [+] Less [-]Junta de Andalucía (US-1380878)
Show more [+] Less [-]Premio Mensual Publicación Científica Destacada de la US. Facultad de Química
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