Carotenoids’ Production from Halophilic Bacteria
2012
Moreno Amador, María de Lourdes | Sánchez-Porro Álvarez, Cristina | García, María Teresa | Mellado Durán, María Encarnación | Universidad de Sevilla. Departamento de Microbiología y Parasitología
Carotenoids have received considerable attention due to their interesting industrial applications and, more importantly, their potential beneficial effects on human health. Halophiles comprise a heterogeneous group of microorganisms that need salts for optimal growth. The pigments produced by these halophilic organisms comprise phytoene, β-carotene, lycopene, derivatives of bacterioruberin and salinixanthin. Here we describe the procedure to obtain salinixanthin from the extremely halophilic bacterium Salinibacter ruber. Moreover, we describe the expression of β-carotene biosynthetic genes crtE, crtY, crtI, and crtB from Pantoea agglomerans in the moderately halophilic bacterium Halomonas elongata obtaining a strain able to produce practically pure β-carotene. Thus, the use of these halophilic microorganisms as a source of carotenoids constitutes an important commercial alternative in the production of carotenoids from biological sources.
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