Cytogenetic Diagnosis of a British Shorthair Tomcat with a 37,X/38,XY/39,XY+der(Y) Karyotype
Kowal Wiktoria | Barbara Kij-Mitka | Kamila Bednarek | Halina Cernohorska | Svatava Kubickova | Monika Bugno-Poniewierska
English. In this study, the determination of three different cell lines in a two-year-old British shorthair tomcat, using fluorescence in situ hybridisation (FISH), is described. The FISH technique was instrumental in the identification of this chromosomal aberration, which had not been previously described in cats. The mosaic karyotype with three cell lines (37,X; 38,XY; and 39,XY+der(Y)), detected using X-, Yand autosomal B1-whole chromosome painting probes, were all visible in the metaphase and interphase nuclei. The ratios of the three cell lines were 3.6%, 85.6% and 10.8%, respectively. In addition, at the time of this examination, the cat had a temperamental disposition that had persisted beyond castration.
Show more [+] Less [-]English. cat, FISH, whole chromosome painting probes
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