Comparative efficacy of formalized, alum precipitated and aluminium hydroxide gel adsorbed bacterin toxoid of Clostridium perfringens type A
1986
Verma, N.D. (ICAR Research Complex for North-Eastern Hills Region, Shillong (India))
The immune response of 4 strains of C. perfringens type A in eight vaccinal preparations was assayed in rabbits by estimating the gamma globulin content. The increase with respect to alumina gel incorporated vaccine of the two local isolates (C-9/82 and C-14/82) causing false blackleg of cattle was recorded upto 99% and 115% rise as compared to F-3795/67 and F-7870/66 strains which gave 33.8% and 38.51% increase respectively on 28th day of vaccination. The alumina gel vaccine was found superior to formalized and alum precipitated vaccine as far as immunity response and duration were concerned. The exploitation of immunogenic properties of the present isolates against gas gangrene and food poisoning in human being and false blackleg of cattle is being suggested
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