Mapping genes in dairy cattle
1989
Cheong, I.C. (Rural Development Administration, Suwon (Korea R.). Livestock Experiment Station) | Yeo, J.S. (Yeongnam Univ., Kyonsan (Korea R.). Coll. of Agriculture)
Mapping of gene locus in dairy cattle is the basic step to manipulate genes for the purpose of developing superior performances. However, we do not know how many genes contribute to the traits and where it is located on the chromosomes. Research for the identification of gene locations in dairy cattle is in infant stage, but successful results in gene mapping in the human and experimental animals had been applied to disease etiology of cancer and gene manipulation. There are two different approaches toward the mapping of genes; (1) Gene transfer of hybrid clones between dairy cattle somatic cells and transformed mutant cells (somatic cell hybridization and chromosome mediated gene transfer), and (2) Direct assignment of genes by in situ hybridization of DNA of a specific type to fixed dairy cattle chromosomes. This study describes the methods and strategies in mapping genes and the present status of the gene maps in dairy cattle
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