An experimental study of glial antigens: Some pathophysiological disorders and changes in CSF proteins induced by them in monkeys
1993
Cupic, D. | Krzalic, Lj. | Dozic, S. (Faculty of Medicine, Belgrade (Yugoslavia))
As an approach for obtaining glial tissue samples, the process of retrograde and transneuronal degeneration of visual neurons in the lateral geniculate nucleus (LGN) of the brain of Rhesus monkeys was used. Imunization of another group of monkeys with the immunogen containing allogenic tissue of LGN, induced an experimental disease of slow and long-term evolution with manifest hypofunction of the thyroid gland. In contrast to the concentration of albumin, transferrin and total proteins, it was found that there was a statistically significant increase of the prealbumin content in the liquor. This may point to more than one origin for this protein.
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