Efficacy of moxidectin against a strain of Ostertagia spp. resistant to ivermectin, albendazole and levamisole
1995
Corba, J. | Varady, M. | Praslicka, J. (Slovenska Akademia Vied, Kosice (Slovakia). Parazitologicky Ustav)
The efficacy of a new antiparasite drug moxidectin (Cydectin injectable 1 %, Cyanamid) against multiple resistant gastrointestinal nematodes of Ostertagia spp. was studied on 16 lambs experimentally infected each with 7,000 larvae. A single subcutaneous application of 0.2 mg.kg** (-1) of moxidectin reduced the number of nematode eggs in faeces by 99.6 % and the number of worms at helminthological dissection by 99.9 % as compared with untreated lambs. Of the adult worms found in abomasa, 91 % were identified as Ostertagia circumcincta and 9 % as Ostertagia trifurcata.
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