Antibacterial and phytochemical studies on Dicoma tomentosa
1995
Khalid, S. | Afza, N. | Rizvi, H.A. | Badar, Y. (PCSIR Lab., Karachi (Pakistan))
Dicoma tomentosa, a member of the compositae family, is an annual shrub and wildly grows in Pakistan, India and Tropical Africa. A mild board spectrum antibacterial activity was found in the extracts of flowers and roots of Dicoma tomentosa. Both flowers and roots and roots at 1000 Mew g/ml conc. have completely inhibited all the tested strains of Shigella but have not shown activity against any Salmonella species. Significant activity was only found in the flowers where 100 Mew g/ml crude extract was sufficient to inhibit completely the growth of S. aureus and E. coli. Leaves have relatively low activity against only few organisms. The whole plant is rich in alkaloids and flavonoids while the concentration of steroids/ triterpenoids, saponins and cuomarins are very low. The biological activity of this plant may be attributed to its alkaloids or flavonoids fractions.
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