Endemic goiter in lambs from Tokachi district in Hokkaido [Japan]
1997
Doi, R. (Obihiro Univ. of Agriculture and Veterinary Medicine, Hokkaido (Japan)) | Furuoka, H. | Matsui, T. | Nakagawa, M. | Yuita, K. | Uzuka, Y. | Sarashina, T.
Forty-eight lambs 5 to 14 months of age reared in Tokachi district, Hokkaido, were investigated for thyroid weight, serum thyroid hormone levels and histopathology. Goiter was detected in 9 cases, 4 diffuse hyperplastic goiter (DHG) and 5 colloid goiters (CG), and 2 cases showed markedly increased thyroid weight. In the 4 DHG cases serum thyroxine (T4) levels were lower, and triiodothyronine (T3) levels were significantly higher, resulting in significantly lower T4/T3 ratios, as compared with the normal range. On the other hand, the T4/T3 ratio was significantly higher in the 5 cases of CG. The goiter lambs from 3 farms were fed with diets marginally low in iodine
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