Beneficial effects of demineralized onion fiber on iron absorption from ferrous sulfate by duodenal loops in rats with various iron status
1998
Kishida, T. (Hokkaido Univ., Sapporo (Japan). Faculty of Agriculture) | Kawamura, T. | Saeki, S. | Kiriyama, S.
We have demonstrated previously that concurrent addition of demineralized onion fiber (DOF), demineralized wheat bran or powdered polystyrene foam to a basal diet containing Fe(II) in the form of ferrous sulfate (20 mg Fe/kg diet) significantly improved hemoglobin regeneration in anemic rats which had been maintained on an iron deficient diet for 3 weeks. A balance study revealed that the addition of DOF improved the apparent absorption of Fe(II). In the present study, we examined the effect of DOF on iron absorption from 59Fe-labeled ferrous sulfate solution (20 mg Fe(II)/L) placed in rat duodenal loops. The addition of DOF (10 mg/mL) to the labeled medium accelerated the absorption of iron irrespective of whether the rats had been maintained on an iron-deficient diet for 14 or 42 days or on an adequate diet (41 mg Fe/kg diet) for 10 days
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