Studies on the toxic interaction between monensin and tiamulin in rats:toxicity and pathology
2000
Szucs, G. | Bajnogel, J. | Varga, A. | Mora, Z. | Laczay, P.
The characteristics of the toxic interaction between monensin and tiamulin were investigated in rats. A three-day comparative oral repeated-dose toxicity study was performed in Phase I, when the effects of monensin and tiamulin were studied separately (monensin 10, 30 and 50 mg/kg or tiamulin 40, 120 and 200 mg/kg body weight, respectively). In Phase II, the two compounds were administered simultaneously (monensin 10 mg/kg and tiamulin 40 mg/kg).
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