Serum and heart phospholipids in rats fed hyperenergetic diet supplemented with margarine and sunflower seed oil-lard mixture
2000
Tepsic, V. | Ristic, V. | Ristic, D. | Ristic, G. | Vrbaski, S. (Institut za medicinska istrazivanja, Beograd (Yugoslavia). Odeljenje za izucavanje ishrane)
The present study investigated the influence of hyperenergetic diet supplemented with margarine and sunflower seed oil-lard mixture on serum and heart phospholipids in rats. We used male Wistar rats, as an experimental model, age 2 months and 200 g weight at the beginning of the experiment. Control (K) group was fed 18 g/day standard laboratory normoprotein-normoenergetic diet. Group M was offered standard diet supplemented with 20g% margarine and group UM was offered standard diet supplemented with 20% sunflower seed oil-lard mixture (1:1), ad libitum. After four weeks feeding hyperenergetic diet supplemented with dietary fat serum phosphatidilcholine and lysophosphatidilcholine content was increased in M group. All investigated phospholipid fractions (lysophosphatidilcholine, sphingophospholipids, phosphatidilcholine and phosphatidilethanolamine) were increased in UM group. In hearts of both experimental groups cardiolipin content was decreased. Phospha-tidilserine and lysophosphatidilcholine content was increased in hearts of UM group. Results show that hyperenergetic diet supplemented with dietary fat had different influence on the phospholipid fractions content in serum and heart of rats dependent upon the type of fat.
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