Renal disease haemogram and plasma biochemistry in green iguana
2002
Knotek, Z. | Hauptman, K. | Knotkova, Z. | Hajkova, P. | Tichy, F. (Veterinarni a Farmaceuticka Univ., Brno (Czech Republic). Fakulta Veterinarniho Lekarstvi)
Haemogram and plasma biochemistry were investigated in 20 green iguanas suffering from renal disease. Anorexia was present in 15 patients, frequently associated with limited hind leg movement (50 %). Constipation as a secondary complication was observed in 8 iguanas. Swelling of the hind legs appeared in 6 iguanas. The post-mortem examination revealed renal oedema, tubular necrosis, tubular and/or interstitial nephritis, renal gout with tophi formation in 62.5 %, 62.5 %, 40 %, and 37.5 % of iguanas, respectively. Evaluation of the haemogram revealed in these patients heterophilia, eosinophilia, and azurophilia. The number of lymphocytes was significantly lower, while the concentrations of creatinine, AST, uric acid, and phosphorus were significantly higher than those of healthy iguanas. The activity of ALP significantly decreased. As a consequence of the elevated phosphorus levels the P:Ca ratio increased significantly to 3.52. Evaluation of the haemogram as well as plasma biochemistry may be regarded as a useful tool in the diagnosis of renal failure in green iguanas.
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