Arrested development of Trichostrongylus colubriformis in experimentally infected rabbits. The effect of acquired resistance, single, multiple doses and size of doses on rise of hypobiosis
2003
Jankovska, I. | Langrova, I. | Vadlejch, J. (Ceska Zemedelska Univ., Prague (Czech Republic). Agronomicka Fakulta)
The effect of size and frequency of infections with Trichostrongylus colubriformis was studied in single or multiple infected rabbits. Groups of 5 rabbits were infected with a single dose of 10,000 infective larvae of T. colubriformis per rabbit or lower multiple infections with or without immunosuppression. All rabbits were killed 20 days after the last infection. The major stimulus to the induction of inhibited development at the early third larval stage (EL3) in the host was the repeated infection with 750 L3 in 5-day-interval with immunosuppression. This infection resulted in a mean of 25.26% of the established worm burden becoming inhibited at the EL3 stage. Another infection did not increase the proportion of worms subsequently found to be hypobiotic.
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