Use of a larval development assay to estimate anthelmintic efficacy in goats in smallholder farming systems
2003
Venturina, V.M. | Ancheta, P.B. (Central Luzon State Univ., Munoz, Nueva Ecija (Philippines). Coll. of Veterinary Science and Medicine) Dodson, R.J. | Eduardo, S.L. | Gray, G.D.
Resistance to benzimidazole anthelmintics was demonstrated in nematodes isolated from faeces of goats in 30 farms in the province of Nueva Ecija, Philippines. The average efficacy was 84% (range 7-100%). The method used to detect resistance was a larval development assay modified from a commercialized research tool, Drenchrite. Faeces were collected from the rectum of each goat or from the ground after collecting groups of goats in a yard or in a shed with slatted floor. Information on herd size, management practices and deworming procedures were obtained from a survey of goat owners. Herd sizes ranged from 3 to 72 goats. No other management or deworming factors were significantly associated with efficacy based on results of the larval development assay. Species belonging to Haemonchus and Trichostrongylus were the most numerous genera present in the faecal samples. Haemonchus tended to be present in higher numbers among the resistant larvae found on the assay plates
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