Biochemical and histopathological effects of carbendazim to rat male reproduction
Barlas, N.(Hacettepe University, Beytepe - Ankara (Turkey). Science Faculty, Department of Biology)) | Selmanoglu, G. | Songur, S. | Kockaya, E.A. | Erdemli, E.
The purpose of this study was to determine the effects of carbendazim (methyl 2-benzimidazole carbamate) on the some hormone levels and on testis tissue. Carbendazim in the doses of 0, 150, 300, and 600 mg/kg/day were administered (by gavage) to male rats, daily for 15 weeks. At the end of the experiment, serum total testosterone and dihydrotestosterone (DHT) levels were analyzed, and testis tissue were taken for light and electron microscopic examinations. The results obtained suggest that carbendazim, in subchronical exposure, affects testis tissue and androgenic hormone levels.
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