Effects of aqueous stem bark extract of Momordica balsamina Linnon serum electrolytes and some hematological parameters in normaland alcohol fed rats
2004
Geidam, M.A. | Pakmam, I. | Laminu, H.,University of Maiduguri,Borno State (Nigeria). Dept. of Biochemistry
In the present study aqueous stem bark extract of Momordicabalsamina was administered intragastrically to normal and alcohol fedrats to determine the effects of the extract on serum electrolytes andsome hematological parameters. The stem bark extract wasadministered for two weeks at a dose of 0.56 mg/100 g body weight.The parameters studied were the major electrolytes (Na+, K+, Cl- andHCO3-), glucose, albumen, total protein and some hematologicalparameters (RBC and WBC counts, PCV and haemoglobin). The resultsobtained showed that serum electrolytes levels were not significantlyaffected and significant effects on hematological parameters (RBCcounts, PCV and haemoglobin) except WBC counts. The stem barkextract produced significant (p less than 0.05) increases in WBC countvalues. This elevation to blood cells count following the administrationof the extract may be an indication of a possible immune response oftreated rats but the implication of this finding on WBC count remainsto be explained.
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