Antioxidant and antitumor activities of ethanol extracts from the fruiting body of Phellinus gilvus grown in oak and artificial sawdust
2005
Hwang, M.H. (Kyungpook National University, Daegu, Republic of Korea) | Kim, Y.H. (Gyeongbuk Veterinary Service Laboratory, Daegu, Republic of Korea) | Jo, W.S. (Gyeongbuk Agricultural Technology Administration, Daegu, Republic of Korea) | Kim, J.C. (Chonnam National University, Gwangju, Republic of Korea) | Kim, K.S. (Kyungpook National University, Daegu, Republic of Korea) | Kim, T.W. (Kyungpook National University, Daegu, Republic of Korea) | Park, S.C. (Kyungpook National University, Daegu, Republic of Korea), E-mail: parksch@knu.ac.kr | Choi, S.G. (Gyeongbuk Agricultural Technology Administration, Daegu, Republic of Korea)
The purpose of this study is to examine the elemental compositions, antioxidant and antitumor activity of water, 20%, 40%, 60%, and 80% ethanol extracts obtained from the fruiting body of Phellinus gilvus. In electron donating ability test, the strong activities more than 70% were observed in 80 μg/ml of 20%, 40%, 60% and 80% ethanol extracts from the fruiting body of P. gilvus grown in oak and sawdust. The antitumor activity was evaluated by sulforhodamine B (SRB) in terms of cell survival level. The tumor cells (sarcoma 180) were treated with various ethanol extracts (water, 20, 40, 60 and 80%). The results showed that all extracts inhibited proliferation showing a dose-dependent manner against tumor cells.
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