Effects of bone healing capacity by autologous fibrin glue in experimental bone defect dogs
2005
Lee, J.I. (Chonbuk National University, Jeonju, Republic of Korea) | Song, H.N. (Chonbuk National University, Jeonju, Republic of Korea) | Kim, N.S. (Chonbuk National University, Jeonju, Republic of Korea), E-mail: namsoo@chonbuk.ac.kr
This study was investigated of the bone healing capacity by autologous fibrin glue in experimental bone defect dogs. The autologous fibrin glue manufactured just before the experiment was mixed with the concentrated fibrinogen from whole blood of the experimental dog and bovine thrombin. The experimental group was constituted with seven dogs. The experimental osteotomy was performed 5 mm length in bilateral region of proximal diaphyseal fibulae. The defected regions of experimental group were filled with the autologous fibrin glue by duploject. The experimental regions had been radiographed biweekly for 16 weeks to observe new bone formation and union.
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