Study of genotoxic effects of pesticides by erythrocyte bone marrow micronucleus assay
2004
Kovalkovicova, N.,Univerzita veterinarskeho lekarstva, Kosice (Slovak Republic). Komenskeho 73, SK-041 01 Kosice | Sutiakova, I.,Univerzita veterinarskeho lekarstva, Kosice (Slovak Republic). Vyskumny ustav veterinarnej mediciny, Hlinkova1/A, SK-040 01 Kosice | Legath, J. | Pistl, J.
The present study emphasizes that the assessment of genotoxic risk arising from xenogenous substances demands the development of sensitive, direct and more exact genotoxic testing methods. One of them is the micronucleus assay in bone marrow erythrocytes. It is a simple and quick test for investigating of cytogenetic damage with the advantage that exposure to both clastogens and aneugens may be detected. The attention has been focused on pesticides that together with heavy metals from emissions are dominant compounds of the chemical load on the environment of man and animals.
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