Efficacy of dietary selenium to counteract toxicity of deoxynivalenol in growing broiler chickens
2007
Faixova, Z.,Univerzita Veterinarskeho Lekarstva, Kosice (Slovak Republic). Ustav Patologickej Fyziologie | Faix, S.,Slovenska Akademia Vied, Kosice (Slovak Republic). Ustav Fyziologie Hospodarskych Zvierat | Borutova, R.,Slovenska Akademia Vied, Kosice (Slovak Republic). Ustav Fyziologie Hospodarskych Zvierat | Leng, L.,Slovenska Akademia Vied, Kosice (Slovak Republic). Ustav Fyziologie Hospodarskych Zvierat
The aim of this study was to evaluate the effect of deoxynivalenol (DON) on plasma indicators and efficacy of dietary selenium to counteract toxicity of DON in growing broiler chicks. Three groups of broilers were formed with 14 birds in each group. Three diets included control (0.2 ppm DON, 0.4 mg Se/kg diet), DON-contaminated (3 ppm DON, 0.4 mg Se/kg diet) and DON-contaminated (3 ppm DON) plus Se-enriched yeast (1.4 mg Se/kg diet) diets. After 6 weeks of feeding all birds were sacrificed and blood samples for chemical analyses were collected. Plasma calcium and chloride concentrations as well as alanine aminotransferase activity were significantly elevated, whereas magnesium, total proteins, triglycerides and free glycerol concentrations were decreased in chicks fed DON-contaminated diet compared with those fed the control diet. Supplementation of Se-enriched yeast to the contaminated diet reversed plasma levels of Ca, Mg and alanine aminotransferase activity. P, albumin and cholesterol levels as well as alkaline phosphatase, aspartate aminotransferase and lactate dehydrogenase activities were not affected. The inclusion of Se to DON-contaminated diet, however, did not completely alleviate its toxic effect on protein and lipid metabolism by the liver. Supplementation of Se-enriched yeast product counteracted most of the plasma indicator alterations caused by DON in chicks.
Show more [+] Less [-]AGROVOC Keywords
Bibliographic information
This bibliographic record has been provided by Library of Antonin Svehla