Studies on stress induced effects in broilers following vaccination (Nobilis Ma5 + Clone 30) against infectious bronchitis and newcastle disease
2000
Syed, S.I. (College of Veterinary Sciences, Lahore (Pakistan))
This study was intended to detect the stress induced by live, freezed-dried vaccine against Newcastle disease and infectious bronchitis disease viruses in broilers and to determine the comparative efficacy of vitamins and aspirin to combat it. One hundred and sixty day-old chicks were divided into four-group i.e. A, B, C and D having 40 birds each. The birds were kept for 42 days after vaccination with Nobilis Ma5+Clone 30 by eye-droppings on 1st and 22nd day of age. Chicks from group A was kept as control. Group B was given vaccine and no treatment. Group C was given vaccine and only vitamins (Vety Stress-Check). Group D was given vaccine and only aspirin. Ten birds from all groups were randomly selected to collect the serum samples from blood on 1st, 14th, 28th and 42nd day of antibody titre determination. The following parameters were studied (i) antibody response against Newcastle disease vaccine, (ii) Serum bio- chemical substances (Total scrum protein, glucose and cholesterol), (iii) Heterophil/lymphocyte ratio, (iv) Adrenal/body weight ratio, (v) Gross histopathology of adrenal glands and (vi) the economics of the flock. The live virus Newcastle disease vaccine had no significant stressor effect on any of the above parameters. However, use of vitamins played vital role in combating the vaccination stress, because it showed immuno competent effect and also positive trend in growth traits. That is why this group showed better economic value than the rest of the groups. The effect of Aspirin was also variable.
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