Generalized symmetric alopecia and hyperoestrogenism associated with concurrent lymphoma, Sertoli cell tumour and seminoma in a samoyed
2007
Plavec, T., Ljubljana Univ. (Slovenia). Veterinary Fac. | Tozon, N. | Kotnik, T.
A 10-year-old Samoyed with unilateral right cryptorchidism was referred to the Clinic for Small Animal Medicine and Surgery, Veterinary Faculty of Ljubljana University, due to a symmetrical, noninflammatory, mildly pruritic alopecia of 6-month duration. It had a history of diarrhoea, which responded to cyclosporine treatment. Lymphoma and testicular neoplasia were suspected based on ultrasonography and fine needle aspiration cytology. The dog was castrated and splenic and gastric lymph node biopsies were obtained. Histopathology revealed three different tumours: Sertoli cell tumour and seminoma were present in the right inguinal testicle, and B cell lymphoma was present in the spleen and lymph node. After two months when the peripheral lymph nodes were considerably enlarged and the owners declined chemotherapy, they were advised to start corticosteroid treatment. Three months after the castration, the hair coat looked normal. Four months after the castration, the dog was euthanized at the owner’s request by the referring veterinarian due to a lymphoma related disease.
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