Liver injury due to 3-amino-1-methyl-5H-pyrido [4,3-b] indole (Trp-P-2) and its prevention by miso

Suzuki, H.; Sone, H.; Kawamura, K.; Ishihara, K.

Liver injury due to 3-amino-1-methyl-5H-pyrido [4,3-b] indole (Trp-P-2) and its prevention by miso

2008

Suzuki, H.(Niigata Women's Coll. (Japan)) | Sone, H. | Kawamura, K. | Ishihara, K.

Trp-P-2(3-amino-1-methyl-5H-pyrido [4,3-b] indole) ingestion for 42 d by C3H/HeJJcl mice caused elevation of serum alanine transaminase (ALT) activity and several signs of liver injury. These alterations were not observed in mice fed the diet supplemented with 10% miso. This suggests a preventive effect of miso as to Trp-P-2 induced liver injury.

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AGROVOC Keywords

administration orale alanina aminotransferasa alanine aminotransferase alimentos fermentados blood serum diet dieta fermented foods foie liver mutagens oral administration soja soybeans

Bibliographic information

Published in

Bioscience, Biotechnology and Biochemistry (Japan)

Volume 72 Issue 8 ISSN 0916-8451

Pagination

pp. 2236-2238

Other Subjects

Serum sanguin; Suero sanguineo; Mutagene; Administracion oral; Higado; Mutagenos; Aliment fermente; Regime alimentaire

Language

English

Note

Summary (En)

1 tab. 1 fig. 22 ref.

Type

Summary

In AGRIS since: 2009-03-15

Format: AGRIS AP

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Liver injury due to 3-amino-1-methyl-5H-pyrido [4,3-b] indole (Trp-P-2) and its prevention by miso

2008

AGROVOC Keywords

Bibliographic information