Detection of swine hepatitis E virus in the porcine hepatic lesion in Jeju Island
2007
Lee, S.H. (Cheju National University, Jeju, Republic of Korea) | Kang, S.C. (Cheju National University, Jeju, Republic of Korea) | Kim, D.Y. (Seoul National University, Seoul, Republic of Korea) | Bae, J.H. (Cheju National University, Jeju, Republic of Korea) | Kim, J.H. (Cheju National University, Jeju, Republic of Korea), E-mail: [email protected]
Swine hepatitis E virus (HEV) is an emerging zoonotic pathogen due to its close genomic similarity to human HEV. The prevalence of swine HEV in the hepatic lesion of pigs from the Jeju Island was investigated by reverse transcriptase polymerase chain reaction (RT-PCR). In total, 40 pigs with hepatitis lesions were selected from 19 different farms, based on examination by microscopy. RT-PCR findings revealed swine HEV in 22 cases (55%), including 18 suckling pigs and 4 growing pigs. Several histopathological lesions, including multifocal lymphoplasmacytic hepatitis, portal inflammation, and focal hepatocellular necrosis, were observed in liver sections of swine HEV PCR-positive pigs.
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