Comparative therapeutic trials against coccidiosis in dogs
2005
Nisar, M.
The faecal samples of two hundred dogs were examined in the Medicine laboratory, by direct smear method, and also concentration technique for identification of Isospora oocyst. Out of two hundred dogs thirty-six were found positive for the coccidial infection, showing the prevalence of Isosporiosis as 18%. For chemotherapeutic trials, thirty naturally infected and ten non-infected dogs were selected and divided randomly into four groups having ten dogs in each groups viz. A, B, C and D. Group A was treated with Co-trimoxazole at the dose rate of 15mg/kg (orally) and group B was treated with Furazolidone at the dose rate of 8mg/kg (orally). Group C was kept as infected non-medicated control. Group D was kept as non-infected and non-medicated control. Faecal samples of experimental dogs were examined for OPG counts on day zero (pre-medication), 3rd, 7th and 10th day of medication and percentage reduction of oocyst was calculated. Co-trimoxazole showed 63%, 90% and 97% efficacy whereas Furazolidone showed 63%, 89.8% and 95% efficacy on day 3, 7 and 10, respectively. Hematological study revealed that the values of haemoglobin and packed cell volume were lower in groups A, B, and C as compared to non-infected control group. Whereas as a result of treatment in-group A and B the values of haemoglobin and packed cell volume gradually increased on day 3, 7 and 10 post-medication. It has been observed during the present study that Co-trimoxazole and Furazolidone showed their effect on blood parameters as a result of curing lsosporiosis.
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