Antifungal (Gaeumannomyces graminis var. tritici) activity of various glycosides of medicagenic acid
2005
Martyniuk, S. | Jurzysta, M.,Instytut Uprawy Nawozenia i Gleboznawstwa, Pulawy (Poland)
Different concentrations of medicagenic acid and five glycosides of this acid isolated from alfalfa (Medicago sativa) were added to agar medium (corn meal agar, CMA) inoculated with cultures of Gaeumannomyces graminis var. tritici (Ggt). After 7 days of incubation at 25 deg C colony radius was measured and percent of inhibition calculated in relation to the control medium (CMA enriched with the solvent of the tested compounds). Within the tested concentrations, only 3-O-beta-D -glucopiranoside medicagenate (monoglucoside) significantly reduced the growth of Ggt on CMA medium. This compound at 0.05 mM concentration completely inhibited the development of the fungus and the effect was shown to be fungi-toxic
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