Inhibitory effects of turmeric (Curcuma longa linn.) extracts on some human and animal pathogenic bacteria | ผลการยับยั้งของสารสกัดขมิ้นชัน (Curcuma longa Linn.) ต่อเชื้อแบคทีเรียก่อโรคบางชนิดในคนและสัตว์บางชนิด
2009
Pornchai Sincharoenpokai(Kasetsart University, Bangkok (Thailand). Faculty of Veterinary Medicine. Department of Microbiology and Immunology) E-mail:[email protected] | Ong-ard Lawhavinit(Kasetsart University, Bangkok (Thailand). Faculty of Veterinary Medicine. Department of Microbiology and Immunology) | Patcharee Sunthornandh(Kasetsart University, Bangkok (Thailand). Faculty of Science. Department of Microbiology) | Ngampong Kongkathip(Kasetsart University, Bangkok (Thailand). Faculty of Science. Department of Chemistry. Natural Products and Organic Synthesis Research Unit) | Suriyan Sutthiprabha(Kasetsart University, Bangkok (Thailand). Faculty of Science. Department of Chemistry. Natural Products and Organic Synthesis Research Unit) | Boonsong Kongkathip(Kasetsart University, Bangkok (Thailand). Faculty of Science. Department of Chemistry. Natural Products and Organic Synthesis Research Unit)
Inhibitory effects of the ethanol turmeric extract, hexane turmeric extract and curcuminoids from the ethyl acetate extract which contained curcumin 86.5 percent, were examined on some human and animal pathogenic bacteria by the Kirby-Bauer method. The ethanol turmeric extract and the hexane turmeric extract showed inhibitory effects against the following 13 bacteria, V. harveyi, V. cholera, V. alginolyticus, V. parahaemolyticus, V. vulnificus, A. hydrophila, Str. agalactiae, Staph. aureus, Staph. epidermidis, Staph. intermidis, B. subtilis, B. cereus and Ed. tarda. The curcuminoids showed inhibitory effect against 8 bacteria which were A. hydrophila, Str. agalactiae, Staph. aureus, Staph. epidermidis, Staph. intermidis, B. subtilis, B. cereus and Ed. tarda in which some were different from those of ethanol and hexane turmeric extract. The MICs of the ethanol turmeric extract, hexane turmeric extract and curcuminoids ranged from 3.91-125, 125-1000 and 3.91-500 ppt, respectively. The results of this investigation appear to indicate that turmeric extract has high potential of inhibitory effect to some human and animal pathogenic bacteria.
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