COMPARATIVE EVALUATION OF SERODIAGNOSTIC TECHNIQUES IN CYSTIC HYDATID DISEASE
2000
DALIMIASL A, A.H., MEDICAL SCIENCES FACULTY,TARBIAT MODARRES UNIVERSITY,TEHRAN, IRAN | MADANI, R., MEDICAL SCIENCES FACULTY,TARBIAT MODARRES UNIVERSITY,TEHRAN, IRAN | GHORBANKHANI, D., MEDICAL SCIENCES FACULTY,TARBIAT MODARRES UNIVERSITY,TEHRAN, IRAN | SALAMI, S., MEDICAL SCIENCES FACULTY,TARBIAT MODARRES UNIVERSITY,TEHRAN, IRAN
Dot-enzyme-linked immunosorbent assay (Dot-ELISA), indirect immunofluorescent antibody (IFA) and indirect haemagglutination(IHA) techniques were used. For detecting anti-echinococcal antibodies caused by Echinococcus granulosus. 246 sera samples including 32 from surgically proved hydatid cyst patients, 104 of patients suffering from a disease other than hydatidosis and 110 from healthy individuals were tested. The results indicate, the Dot-ELISA with 100% sensitivity and 99.5% specificity was more sensitive and specific than other tests. IFA test with 90.6% sensitivity and 96.3% specificity as well as the IHA test with 78.1% sensitivity and 93.9% specificity was found inferior to Dot-ELISA assay, respectively.
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