Enhancement of the antifungal activity of silver ion agents by the addition of plant extracts
2009
Mori, Y., Japan. Ministry of Defense, Sayama, Saitama. Air Self-Defense Force | Ono, T. | Miyahira, Y. | Ishihara, M. | Tanaka, Y. | Hattori, H. | Nakamura, S. | Kishimoto, S. | Matsui, T.
Antimicrobial and antifungal activities of silver ion agents and plant extracts were investigated. Against both Aspergillus niger and Penicillium funiculosum, the antifungal activity of the silver ion agents was enhanced by mixture with the plant extracts, decreasing the minimum inhibitory concentrations of the silver ion agents by at least one-third. The antimicrobial activity against Escherichia coli and the cytotoxicity against human fibroblast cells of the mixture of the silver ion agents and the plant extracts were influenced by the concentration of the plant extracts. The antimicrobial and antifungal activities and the cytotoxicity of the silver ion agents were not affected by phytic acid, which was added as a stabilization agent for the silver ions.
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