Antihypertensive effect of honey-based beverage containing fermented rice bran in spontaneously hypertensive rats
2010
Hiwatashi, K., Akita-ken. Research Inst. of Food and Brewing (Japan) | Narisawa, A. | Hokari, M. | Toeda, K.
The effect of oral administration of a honey-based beverage containing gamma-aminobutyric acid (GABA)-fermented rice bran on blood pressure was investigated in spontaneously hypertensive rats. The control beverage or beverage containing GABA (10.1 mg/kg per day) was administered to 12-week-old male rats for 8 weeks. After 3 weeks administration, blood pressure in rats administered the GABA beverage was lower than that in the control group, while it was significantly decreased on week 7 (218 vs. 234 mmHg, P0.05). In conclusion, oral chronic administration of the GABA beverage to spontaneously hypertensive rats appears to be beneficial and may improve hypertension.
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