Antibacterial Activities of Et-OH Extract from Extruded White Ginseng on Tooth Decay Bacteria
2009
Son, H.J., Kongju National University, Yesan, Republic of Korea | Han, M.S., Hyejeon College, Hongseong, Republic of Korea | Ryu, G.H., Kongju National University, Yesan, Republic of Korea
In this study, antibacterial activity of extruded ginseng extract by 60 and 80% Et-OH were investigated by agar diffusion assay against two bacteria causing dental caries (Streptococcus mutans and Lactobacillus casei). Extrusion conditions were 20% moisture content 100℃ and 140℃ barrel temperature. The inhibition effect of 60% Et-OH ginseng extract was higher than 80% Et-OH ginseng extract. The minimum inhibitory concentration (MIC) of 80% Et-OH extruded ginseng extract at 140 and 100℃ barrel temperature against L.casei were 100 and 150 mg/mL respectively using broth assay method. The amount of glucosyltransferase (GTase) inhibitory content was the highest in extruded ginseng at 140℃ barrel temperature with 60% Et-OH. Moreover, n-hexane and n-butanol fraction ginseng extract had potential against tested bacteria. Our results demonstrated that antibacterial activities of extruded ginseng extract at 140℃ barrel temperature were more effective than Ex-100℃, RG and WG.
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