Spectral changes of brain activity in rat offspring exposed to aluminium during gestation and lactation
2010
Martac, L., Institute for Biological Research Sinisa Stankovic, Belgrade (Serbia) | Grbic, G., Institute for Biological Research Sinisa Stankovic, Belgrade (Serbia) | Kekovic, G., Institute for Biological Research Sinisa Stankovic, Belgrade (Serbia) | Podgorac, J., University of Kragujevac, Kragujevac (Serbia). Medical Faculty | Culic, M., Institute for Biological Research Sinisa Stankovic, Belgrade (Serbia) | Sekulic, S., University of Novi Sad, Novi Sad (Serbia). Faculty of Medicine | Lalosevic, D., University of Novi Sad, Novi Sad (Serbia). Faculty of Medicine | Capo, I., University of Novi Sad, Novi Sad (Serbia). Faculty of Medicine
Exposure to aluminium during gestation causes changes in mammalian brain development and behaviour. The aim of this study was to perform spectral analysis on electrocortical activity of Sprague Dawley male pups (30+/-3 days of age) whose mothers were treated with aluminium during gestation and lactation. There was a higher presence of power spectra in the delta range of parietal electrocortical activity, a lower presence in the theta range and increased values of the parameter DT as the ratio of delta to theta range in pups indirectly exposed to aluminium (whose mothers were drinking a 0.5% water solution of aluminium chloride during the gestation and lactation periods), compared to controls.
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