Использование теотропина для инактивации вируса болезни Ауески при конструировании инактивированной вакцины
2009
Chaplygo, K.Eh. | Gusev, A.A., National Academy of Sciences. Scientific and Practical Center of Animal Breding (Belarus). The S.N. Vyshelesskij Inst. of Experimental Veterinary Medicine
A description of a method of chemical inactivation of Aujeszky's disease virus by teotropin was studied in the conditions of the Republic of Belarus. The developed inactivated viral suspension was tested for its antigenic activity. On the basis of realized experiments there were determined the optimal parameters of inactivation of Aujeszky's disease virus y means of 0,1% solution of teotropin under temperature of 37 deg C, pH 7,8 and duration of exposition of 24 hours. There were studied indexes of antigenic activity of inactivated virus
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