Влияние антигельминтиков различных групп на микрофлору и микрофауну желудочно-кишечного тракта крупного рогатого скота
2009
Subbotina, I.A., Vitebsk State Academy of Veterinary Medicine (Belarus)
Determination of influence of long acting antihelminthics (Aversictini boluses and boluses with albendazole) and influence of usual antihelminthics (farmatsin, alverm, fenbendavet) on first stomachanimal digestion, as well as on quantity and quality composition of microflora and microfauna in first stomach and large bowel was realized in the conditions of the Republic of Belarus. In course of the experiment there were used 6 groups of calves infested with helminths (Neoascaris vitulorum, Strongylata sp.). Research result showed that different antihelminth preparations to a greater or lesser degree rendered negative influenced on quantity and quality composition of microorganisms in first stomach and large bowel of cattle. Alverm and boluses with albendazole rendered the least influence on microflora and microfauna that could be explained by low toxicity of active substance (albendazole) of the above preparations. Aversictini boluses, fenbendavet, and farmastin changed the composition of microorganisms. It could be explained by high toxicity of preparations containing aversictini which rendered influence not only of gastro-intestinal tract but also on the whole organism. Active ingredient of mentioned above preparations (Aversektin C), being the product of microbial synthesis, rendered the antagonist action on the normal microflora of digestive tract. Negative influence of fenbendavet was caused by the chemical composition of the preparation and neurotoxic action of fenbendazol
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