Intestinal mucin dynamic and leukocytic responses of chickens infected with Eimeria acervulina and fed oregano supplemented diet
2011
Major, P.,Univerzita Veterinarskeho Lekarstva a Farmacie, Kosice (Slovak Republic). Katedra Epizootologie a Parazitologie | Revajova, V.,Univerzita Veterinarskeho Lekarstva a Farmacie, Kosice (Slovak Republic). Katedra Patologickej Anatomie a Patologickej Fyziologie | Levkut, M.,Univerzita Veterinarskeho Lekarstva a Farmacie, Kosice (Slovak Republic). Katedra Patologickej Anatomie a Patologickej Fyziologie | Sevcikova, Z.,Univerzita Veterinarskeho Lekarstva a Farmacie, Kosice (Slovak Republic). Katedra Patologickej Anatomie a Patologickej Fyziologie | Spisakova, V.,Univerzita Veterinarskeho Lekarstva a Farmacie, Kosice (Slovak Republic). Katedra Epizootologie a Parazitologie | Faixova, Z.,Univerzita Veterinarskeho Lekarstva a Farmacie, Kosice (Slovak Republic). Katedra Patologickej Anatomie a Patologickej Fyziologie | Levkutova, M.,Univerzita Veterinarskeho Lekarstva a Farmacie, Kosice (Slovak Republic). Katedra Epizootologie a Parazitologie | Kozarova, I.,Univerzita Veterinarskeho Lekarstva a Farmacie, Kosice (Slovak Republic). Ustav Hygieny a Technologie Masa | Goldova, M.,Univerzita Veterinarskeho Lekarstva a Farmacie, Kosice (Slovak Republic). Katedra Epizootologie a Parazitologie | Levkut, M.,Univerzita Veterinarskeho Lekarstva a Farmacie, Kosice (Slovak Republic). Katedra Patologickej Anatomie a Patologickej Fyziologie
We studied the effect of oregano supplemented to the diet of broiler chickens on mucin dynamics in small intestine, peripheral blood leukocytes and jejunal immunocompetent cells. ROSS 308 hybrid broilers were infected with Eimeria acervulina chickens' oocyst. From the day of hatching chicks of groups 1 and 2 were fed a commercial diet without anticoccidial drug, the diet of group 3 was supplemented with oregano (0.707 g/kg), and that of group 4 with anticoccidial drug (Robenidin hydrochloride - 33 mg/kg). Chickens of groups 2, 3, and 4 were inoculated with E. acervulina oocysts (25 x 10**3) on day 12. The samples were collected on 3, 10, 17 days post infection (dpi). In blood on 3 dpi significant increase of leukocytes was found in group 3 compared to groups 1, 2, and 4, higher density of IgM+ cells in group 3 than in group 2, and on 10 dpi phagocytic activity of group 3 was higher than that of group 1. Number of jejunal CD4+ and CD8+ cells in group 3 was consistent with values in group 4, despite a higher density of E. acervulina meronts on 10 dpi. The quantity of jejunal mucin adherent layer of group 3 was similar to that in group 4. Counts of oocysts in faeces were lower in group 3 than group 2. Results suggest that dietary supplementation of oregano to chickens infected with E. acervulina has a modulating effect on some blood indicators and functions of phagocytes. The beneficial effect of oregano components on jejunal mucin quantity and its turnover is the first finding published in relation to oregano and coccidia.
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