Antimicrobial potential of gemmo-modified extracts of Terminalia arjuna and Euphorbia tirucalli
2011
Jahan, N. (University of Agriculture, Faisalabad (Pakistan). Dept. of Chemistry and Biochemistry) | Khalil-ur-Rehman (University of Agriculture, Faisalabad (Pakistan). Dept. of Chemistry and Biochemistry) | Ali, S. (University of Agriculture, Faisalabad (Pakistan). Dept. of Chemistry and Biochemistry) | Bhatti, I.A.
The present study was conducted to investigate the in vitro antimicrobial potential of two medicinal plants Terminalia arjuna and Euphorbia tirucalli. Antimicrobial activity of methanolic, acetone, ethyl acetate, water and gemmomodified extracts of both plants was determined by using disc diffusion method against four bacterial (Bacillus subtilis, Staphylococcus aureus, Escherichia coli & Pasteurella multocida) and two fungal strains (Rhizopus solani, Aspergillus niger). Gemmomodified extract of T. arjuna showed broad spectrum antimicrobial potential. Strongest activity was detected with gemmomodified extract of Terminalia arjuna against Bacillus subtilis at the concentration of 1000 mug disc-1. T. arjuna strongly inhibited the growth of tested fugal strains at all concentrations. Highest effect with methanolic extract of E. tirucalli was observed against S. aureus and B. subtilis at the concentration of 1000 mug. Gemmomodified extract of E. tirucalli was more effective against E. coli and strongly inhibited the growth of fungal strains. Gemmomodified extracts of both plants showed higher inhibitory effect on all tested microbial strains than other extracts.
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