Determination of parameters of non-specific immunity in the course of parvovirus disease in dogs
2011
Bečárová, L., University of Veterinary Medicine and Pharmacy in Košice (Slovak Republic) | Vojtek, B. | Smrčo, P. | Mojžišová, J. | Hipíková, V.
Parvovirus disease of dogs caused by canine parvovirus type 2 CPV2)is an acute, highly contagious disease manifested by gastroenteritis, myocarditis and immunosuppression. This investigation was carried on 6 anonymous puppies, 6—8 weeks old with clinical signs of parvovirosis and the confirmed presence of CPV2 in their faeces(rapid CPV Ag test Kit, Bionote, Korea). The parameters of non-specific immunity were determined and evaluated in these animals during their treatment and convalescence. Puppies with confirmed parvovirosis showed, a decreased index of metabolic activity (IMA) stimulation index (SI) of lymphocytes, chemotactic activity (CHA), increased phagocytic index of leukocytes, and phagocytic activity of neutrophils compared to the control dogs which were negative for CPV2.
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